The long-gestating project is focused on one of the webslinger’s most notorious antagonists, previously brought to life in Spider-Man 3 by Topher Grace.
The film will be directed by Ruben Fleischer, whose credits include Zombieland and, most recently, episodes of the Drew Barrymore comedy Santa Clarita Diet.
Venom will be part of a new Spider-Man universe that was briefly teased in Captain America: Civil War, which introduced Tom Holland as the latest iteration of Peter Parker.
Hardy will play Eddie Brock, a freelance photographer who becomes infected by an alien lifeform that needs a host in order to survive.
The script will come from Scott Rosenberg and Jeff Pinkner.