A 9-year-old South African child diagnosed with HIV when he was 1 month old has been in HIV remission for 8½ years -- without regular treatment. - From KPRC
The child, who was not identified, was part of a study known as the Children with HIV Early Antiretroviral Therapy, or CHER, trial, which ran from 2005 to 2011.
Three adults have also been reported to achieve remission to date, known as the Boston patients and Berlin patient, but all received bone marrow transplants for this result, not early treatment with antiretroviral drugs.
Violari agrees that this new remission case is not applicable to all infants with HIV, but instead that something unique about his biology and immune system helped him protect himself from the virus, aided by starting treatment early.
Her team now hopes to investigate the child, and others from the original CHER trial along with HIV-negative children to try to elucidate just what is unique about the biology enabling a child who has been treated to then suppress the virus indefinitely -- and independently -- known as a post-treatment controller.
"We have the outcome, we just need to get there." "We are delighted and excited by what happened with this child ...