A New Approach To Personalized Cancer Vaccination
Comparing them to control vaccines that lacked PEI but had all the other components, the team found them considerably more efficient in activating DC populations, stimulating interactions with T cells in nearby lymph nodes and driving the generation of circulating killer T cells that recognize tumor-specific peptides. Impressively, a single injection of the vaccine led to rapid and complete eradication of HPV tumors in mice, with 80 percent of the animals living longer than 150 days. Even six months after the injection, the animals vaccinated with the PEI formulation could still destroy tumor cells, showing that they had formed a robust immunological memory of the tumors. Each antibody (immune response) is specifically produced by the immune system to match an antigen after cells in the immune system come into contact with it; this allows a precise identification or matching of the antigen and the initiation of a tailored response. The large surface area of the pores allows the particles to be filled with a drug or a cytotoxin.
Personal cancer vaccines eliminated HPV tumors in mice | NextBigFuture.com
Harvard researchers describe a vaccine approach that uses an injectable scaffold loaded with a selection of tumor-expressed peptides. Comparing them to control vaccines that lacked PEI but had all the other components, the team found them considerably more efficient in activating DC populations, stimulating interactions with T cells in nearby lymph nodes and driving the generation of circulating killer T cells that recognize tumor-specific peptides. Impressively, a single injection of the vaccine led to rapid and complete eradication of HPV tumors in mice, with 80 percent of the animals living longer than 150 days. Even six months after the injection, the animals vaccinated with the PEI formulation could still destroy tumor cells, showing that they had formed a robust immunological memory of the tumors. Impressively, a single injection of the MSR–PEI vaccine using an E7 peptide completely eradicated large, established TC-1 tumors in about 80% of mice and generated immunological memory.
Australia’s cervical cancer vaccine might eradicate the disease
Australia is on track to become the first country to practically eradicate cervical cancer. A national school-based vaccination programme has seen a sharp decline in human papillomavirus (HPV) infections, which cause over 99 per cent of cervical cancer cases. Since 2007, all girls aged 12 or 13 in Australia have been offered a free HPV vaccination. A decade later, the proportion of 18- to 24-year-old women with HPV has fallen from 22.7 to 1.5 per cent.
Cuba develops world’s first lung cancer vaccine
Cuba has developed the world’s first lung cancer vaccine. The vaccine has become the first Cuban-patented drug to be allowed to undergo clinical trials at a cancer research institute in the United States. After undergoing intensive chemotherapy, she is now being treated with the world’s first lung cancer vaccine. What’s different about the vaccine is that it helps the body generate its own immune system in a way that starves the cancer and stops it growing. Danay Saavedra is a senior scientist involved in the lung cancer vaccine and other projects at the Center for Molecular Immunology.

'Universal cancer vaccine' breakthrough claimed by experts

Wtf, Cuba's had a $1 lung cancer vaccine the whole time???

It's the small things in life!

